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Graduate Researchers and Mentors

In Dr. Julie Oxford's LabBoise State University Graduate Students
 

 

 

 

Graduate Students in Dr. Julie Oxford's Lab

Mentors and Graduate Students:
Elizabeth Barney-Smith PortraitDr. Elisa H. Barney-Smith-Associate Professor Electrical and Computer Engineering  Department  Musculoskeletal Research at Boise State University.  Knowledge of the movement and forces on joints during motion and loading can be obtained by the combination of 3D static images and 2D images taken during dynamic activities. The correct relative positioning of the 2D image with respect to the 3D volume enables dynamic information to be extracted from the static 3D image. Methods of doing this are under development for both CT/Fluoroscopic image pairs and MRI images in the BSU Signal Processing Lab. 
CJ Stanger- Ultrasound imaging of the spine to determine spinal compression.
Thanh Tran- Counting tumor cells in a series of microscope images of cells on a slide.
Nazia Sarang-Currently building a GUI (Graphical User Interface) to illustrate how 2D fluoroscopic images can be combined with 3D Computer Tomography (CT) images to allow researchers to get 3D temporal information from which they can study and diagnose joint problems. Biomedical researchers constantly search for new methods to diagnose the extent of joint injuries in live human subjects. In order to achieve this, the researchers need to know the accurate three dimensional kinematic data of bones and joints and to accurately quantify how bones in a joint move relative to one another during dynamic activities. Algorithms have been developed previously to estimate the exact spatial position and movement of the bones. These methods matched three dimensional images of human joints with two dimensional video fluoroscopy (video X-ray) image sequences to track the motions of bones at a joint very accurately. The current project is about developing a user friendly GUI and displaying the bones in both three dimensional and two dimensional space, allowing the human user to do the search which was previously done automatically by the computer using visual information. The user of the GUI can estimate the position of the bone, given images of a bone in three dimensional and two dimensional space. This GUI will allow a non-researcher or student to understand the scope of the problem that researchers are working on to get computers to do automatically.
Cheryl L. Jorcyk- Ph.D. Associate Professor of BiologyCheryl Jorcyk   Cancer and chemotherapy, Diseases of Aging, Musculoskeletal, Biochemistry, Bioinformatics.    
Graduate Student Ken TawaraKen Tawara- Tawara's research at boise state entails trying to clarify the role of (Oncostatin M) OSM in breast cancer in bone metastases. Specifically I am trying to find how OSM increase one destruction when breast cancer cells metastasize to the bone. We found out that OSM increases the expression of various factors by breast cancer cells which could be targeted by novel therapeutics.   
Hunter Covert- Currently studying the effects of OSM (Oncostatin M) on the EMT/MET (Epithelial to Mesenchymal Transition / Mesenchymal to Epithelial Transition) process of breast cancer metastasis.  He is looking at the signaling pathways that drive breast cancer cells to transition from and epithelial morphology to a mesenchymal morphology.  Once breast cancer cells have converted to a mesenchymal state the cells are free to invade the blood stream and travel to other sites within the body. 
Ken CornellKen Cornell- Associate Professor of Biochemistry Cancer and chemotherapy, Infectious Diseases, Biochemistry, Bioinformatics.   Antibiotic Development Targeting Bacterial Communication. Bacteria secrete a variety of small molecule autoinducers that are used to com-municate population wide changes in gene expression that govern such things as virulence factor production and biofilms. We are examining small molecule inhibitors of the enzyme 5’ Methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTN) from a variety of bacterial pathogens for their ability to block enzyme activity and subsequent autoinducer signaling events. A variety of techniques are being used including molecular modeling, spectrophotometry, gene cloning, confocal microscopy and mass spectrometry.  Dr. Cornell currently has two graduate students.
Kristen MitchellKristen Michell-Assistant Professor, Department of Biological Sciences Cancer and chemotherapy, Musculoskeletal, Infectious Diseases, Biomaterials, Biochemistry, Bioinformatics Toxicology.  Dioxins and related compounds are persistent environmental contaminants that elicit toxicity by activating the aryl hydrocarbon receptor.  Current research efforts strive to identify receptor-mediated signaling events and protein-protein interactions that contribute to altered cell cycle progression and immunotoxicity.      Chris Horras-focuses on the role of the innate immune system in liver regeneration and dioxin toxicity.

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