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Boise State University has seen significant growth in external funding for research and sponsored projects, increasing 47% since 2000. During fiscal year 2007, Boise State received $26.8 million in sponsored project funding, a new university record and an increase of $3 million over the previous year. Alzheimer’s Disease: Causes of Cell Death Infectious Disease: Vaccine Development Breast Cancer: Molecular Basis of Tumor Progression Immune System and Inflammation Drug Development: Cancer Chemotherapeutics Arthritis and Rheumatic Diseases Programmable Molecular Rearrangement Processes
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Alzheimer’s Disease: Causes of Cell Death Dr. Troy Rohn
The fluorescent markers indicate the
presence in neural astrocytes of fragments resulting from the activity of
executioner caspases, which are active in the beginnings of the apoptosis that
will, in the long term, result in dementia. |
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Infectious Disease: Vaccine Development Dr. Juliette Tinker Bacterial enterotoxins are potent mucosal
immune stimulators. Boise State researchers are fusing the non-toxic subunit of
Cholera Toxin to a protein from a pathogen of interest to create a mucosal
vaccine. Under development are potential vaccines against Vibrio cholerae,
Helicobacter pylori and Yersinia pestis. Vaccines also have the
potential to fight autoimmune disease and cancer. |
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Breast Cancer: Molecular Basis of Tumor Progression Studies to understand the process of cancer metastasis at the molecular level are essential in developing effective treatments and detection methods. Work at Boise State indicates that Oncostatin M facilitates angiogenesis and metastasis, an observation that is likely to change the present view of this compound as a potential therapeutic drug. |
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Immune System and Inflammation BSU researchers study how regulators of the immune system contribute to the pathogenesis of asthma. β-adrenergic agonists found in common asthma medications alter the regulation in asthma subjects compared to healthy control subjects. |
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Dr. William Knowlton, Dr. Byung Kim Boise State is home to three Atomic Force Microscopes; two housed in Materials Science Engineering and one in Physics. They are integral to interdisciplinary research at Boise State into the development of biomaterials and nanotechnology. |
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Drug Development: Cancer Chemotherapeutics Dr. Henry Charlier,
Dr. Susan Shadle
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Arthritis and Rheumatic Diseases
Extracellular matrix assembly and
organization is key in biological materials structure and function. Age-related
changes to the composition and organization of cartilage contribute to
arthritis; changes in the vitreous of the eye may lead to retinal detachment and
lens cataracts. |
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Programmable Molecular Rearrangement Processes There are numerous examples in cellular biology. Dr.
Scheeper's current project is an investigation of gene scrambling in
hypotrichous ciliates. Potential applications include new computing technology,
and construction of nano-robots. |
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| Gongxin Yu Interested in developing computational algorithms for deriving information and new knowledge from large-scale biological data, including genomi sequence data, microarray gene expression data, proteomic data, etc., and apply such computational tools to solve real biological problems including Text-Mining to build content-rich relationship networks among biological concepts. |
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| Bernard Yurke Research interests are varied, but currently my focus is on DNA nanotechnology and the use of DNA self-assembly to fabricate electrical and optical devices and circuits with a few nanometer feature size. |
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Tim (Tieqiao) Zhang |
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| Jeunghoon Lee Many inorganic materials in nanometer size scale exhibit unique properties that are not only scientifically intriguing but also technologically significant. These nanoparticles, however, have to be incorporated into architectures that provide specific functionality. Goal of my research is to 1) synthesize and fabricate nanoparticles with high degree of architectural control, 2) investigate fundamental physical and optical properties of the nanoparticles, and 3) devise methodologies to assemble functional structures from nanoparticle building blocks. Combining these capabilities new tools for biological sensing and analysis can be developed. |
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| Linda Ransdell | |||
| Eric Dugan | |||
| Jennifer Smith | |||
| Shawn Simonson | |||
| Ko Sasaki | |||
| Michelle Sabick | |||
| Alex Punnoose | |||
| Ronald Pfeiffer | |||
| Owen McDougal | |||
| Kristen Mitchell | |||
| Amit Jain | |||
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Science, engineering, and art are respectively the pursuit, application, and expression of knowledge. Perceived as independent, these vocations are intimately linked through creativity and imagination. Although the interdependence of these fields is historically undeniable [1], the established cultures and vernacular used within each discipline often promote isolation; thereby retarding the exchange of information and progress. The life long goal of Dr. Hughes is to work along the frontiers of these seemingly distinct fields to help expedite the exchange of information between science, engineering, and art, as well as challenge the boundaries by which they have been confined. Once barriers are perforated, new fields of study will emerge that may shed light on historically unresolved questions and lead to solutions never before imagined. |
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| Greg Hampikian | |||
| Jennifer Forbey | |||
| Hilary Flint-Wagner | |||
| Ken Cornell | |||
| Janet Callahan | |||
| Eric Brown | |||
| Elisa Barney Smith | |||
| Tim Andersen | |||
| Abdelkrim Alileche | |||
| Merlin White | |||
